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Sirt1 restrains lung inflammasome activation in a murine model of sepsis
Excessive inflammation is a major cause of organ damage during sepsis. The elderly are highly susceptible to sepsis-induced organ injury. Sirt1 expression is reduced during aging. In the present study, we investigated the role of Sirt1, a histone deacetylase, in controlling inflammatory responses in...
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| Опубликовано в: : | Am J Physiol Lung Cell Mol Physiol |
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| Главные авторы: | , , , , , |
| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
American Physiological Society
2015
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4398874/ https://ncbi.nlm.nih.gov/pubmed/25659903 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajplung.00274.2014 |
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