Activation of the renin-angiotensin system stimulates biliary hyperplasia during cholestasis induced by extrahepatic bile duct ligation

Cholangiocyte proliferation is regulated in a coordinated fashion by many neuroendocrine factors through autocrine and paracrine mechanisms. The renin-angiotensin system (RAS) is known to play a role in the activation of hepatic stellate cells and blocking the RAS attenuates hepatic fibrosis. We inv...

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Pubblicato in:Am J Physiol Gastrointest Liver Physiol
Autori principali: Afroze, Syeda H., Munshi, Md Kamruzzaman, Martínez, Allyson K., Uddin, Mohammad, Gergely, Maté, Szynkarski, Claudia, Guerrier, Micheleine, Nizamutdinov, Damir, Dostal, David, Glaser, Shannon
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Physiological Society 2015
Soggetti:
Liver and Biliary Tract
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4398845/
https://ncbi.nlm.nih.gov/pubmed/25678505
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpgi.00116.2014
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