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Skeletal muscle insulin resistance in zebrafish induces alterations in β-cell number and glucose tolerance in an age- and diet-dependent manner
Insulin resistance creates an environment that promotes β-cell failure and development of diabetes. Understanding the events that lead from insulin resistance to diabetes is necessary for development of effective preventional and interventional strategies, and model systems that reflect the pathophy...
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Vydáno v: | Am J Physiol Endocrinol Metab |
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Hlavní autoři: | , , , |
Médium: | Artigo |
Jazyk: | Inglês |
Vydáno: |
American Physiological Society
2015
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Témata: | |
On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4398831/ https://ncbi.nlm.nih.gov/pubmed/25670827 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpendo.00441.2014 |
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