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Skeletal muscle insulin resistance in zebrafish induces alterations in β-cell number and glucose tolerance in an age- and diet-dependent manner
Insulin resistance creates an environment that promotes β-cell failure and development of diabetes. Understanding the events that lead from insulin resistance to diabetes is necessary for development of effective preventional and interventional strategies, and model systems that reflect the pathophy...
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Publicado no: | Am J Physiol Endocrinol Metab |
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Main Authors: | , , , |
Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
American Physiological Society
2015
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4398831/ https://ncbi.nlm.nih.gov/pubmed/25670827 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpendo.00441.2014 |
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