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ACEI attenuates the progression of CCl(4)-induced rat hepatic fibrogenesis by inhibiting TGF-β1, PDGF-BB, NF-κB and MMP-2,9

AIM: Angiotensin II has pro-fibrotic function in the liver. Blockade of the renin-angiotensin-aldosterone-system (RAAS) attenuates hepatic fibrosis. The aim of the present study was to determine the mechanism of angiotensin-converting enzyme inhibitor (ACEI) on the progression of rat hepatic fibrosi...

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Enregistré dans:
Détails bibliographiques
Publié dans:World J Gastroenterol
Auteurs principaux: Li, Xu, Meng, Ying, Yang, Xi-Shan, Mi, Ling-Fei, Cai, Shao-Xi
Format: Artigo
Langue:Inglês
Publié: Baishideng Publishing Group Inc 2005
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4398726/
https://ncbi.nlm.nih.gov/pubmed/16097048
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3748/wjg.v11.i31.4807
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