Genetic Structures of Population Cohorts Change with Increasing Age: Implications for Genetic Analyses of Human aging and Life Span

BACKGROUND: Correcting for the potential effects of population stratification is an important issue in genome wide association studies (GWAS) of complex traits. Principal component analysis (PCA) of the genetic structure of the population under study with subsequent incorporation of the first severa...

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Udgivet i:Ann Gerontol Geriatr Res
Main Authors: Yashin, Anatoliy I., Wu, Deqing, Arbeev, Konstantin G., Arbeeva, Liubov S., Akushevich, Igor, Kulminski, Alexander, Culminskaya, Irina, Stallard, Eric, Ukraintseva, Svetlana V.
Format: Artigo
Sprog:Inglês
Udgivet: 2014
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4398390/
https://ncbi.nlm.nih.gov/pubmed/25893220
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