Genetic Structures of Population Cohorts Change with Increasing Age: Implications for Genetic Analyses of Human aging and Life Span

BACKGROUND: Correcting for the potential effects of population stratification is an important issue in genome wide association studies (GWAS) of complex traits. Principal component analysis (PCA) of the genetic structure of the population under study with subsequent incorporation of the first severa...

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Pubblicato in:Ann Gerontol Geriatr Res
Autori principali: Yashin, Anatoliy I., Wu, Deqing, Arbeev, Konstantin G., Arbeeva, Liubov S., Akushevich, Igor, Kulminski, Alexander, Culminskaya, Irina, Stallard, Eric, Ukraintseva, Svetlana V.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2014
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4398390/
https://ncbi.nlm.nih.gov/pubmed/25893220
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