The Role of Lipoprotein-Associated Phospholipase A₂ in a Murine Model of Experimental Autoimmune Uveoretinitis

Macrophage activation is, in part, regulated via hydrolysis of oxidised low density lipoproteins by Lipoprotein-Associated phospholipase A(2) (Lp-PLA(2)), resulting in increased macrophage migration, pro-inflammatory cytokine release and chemokine expression. In uveitis, tissue damage is mediated as...

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Udgivet i:PLoS One
Main Authors: Crawford, G. L., Boldison, J., Copland, D. A., Adamson, P., Gale, D., Brandt, M., Nicholson, L. B., Dick, A. D.
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2015
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4398387/
https://ncbi.nlm.nih.gov/pubmed/25874928
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0122093
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