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Agonist antibodies to TNFR molecules that costimulate T and NK cells
Therapy of cancer can be achieved by artificially stimulating anti-tumor T and NK lymphocytes with agonist monoclonal antibodies. T and NK cells express several members of the Tumor Necrosis Factor-receptor (TNFR) family specialized in delivering a costimulatory signal on their surface. Engagement o...
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| Veröffentlicht in: | Clin Cancer Res |
|---|---|
| Hauptverfasser: | , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2013
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4397897/ https://ncbi.nlm.nih.gov/pubmed/23460535 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-12-2065 |
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