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Agonist antibodies to TNFR molecules that costimulate T and NK cells

Therapy of cancer can be achieved by artificially stimulating anti-tumor T and NK lymphocytes with agonist monoclonal antibodies. T and NK cells express several members of the Tumor Necrosis Factor-receptor (TNFR) family specialized in delivering a costimulatory signal on their surface. Engagement o...

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Detalhes bibliográficos
Publicado no:Clin Cancer Res
Main Authors: Melero, Ignacio, Hirschhorn-Cymerman, Daniel, Morales-Kastresana, Aizea, Sanmamed, Miguel F., Wolchok, Jedd D.
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4397897/
https://ncbi.nlm.nih.gov/pubmed/23460535
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-12-2065
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