Llwytho...
A combination Alzheimer’s therapy targeting BACE1 and neprilysin in 5XFAD transgenic mice
BACKGROUND: Accumulating evidence indicates that partial inhibition of β-site APP-cleaving enzyme 1 (BACE1), which initiates amyloid-β (Aβ) production, mitigates Alzheimer’s disease (AD)-like pathologies and memory deficits in a battery of transgenic mouse models. However, our previous investigation...
Wedi'i Gadw mewn:
| Cyhoeddwyd yn: | Mol Brain |
|---|---|
| Prif Awduron: | , |
| Fformat: | Artigo |
| Iaith: | Inglês |
| Cyhoeddwyd: |
BioMed Central
2015
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| Pynciau: | |
| Mynediad Ar-lein: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4397831/ https://ncbi.nlm.nih.gov/pubmed/25884928 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13041-015-0110-5 |
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