Immune cell-based screening assay for response to anticancer agents: applications in pharmacogenomics

BACKGROUND: Interpatient variability in immune and chemotherapeutic cytotoxic responses is likely due to complex genetic differences and is difficult to ascertain in humans. Through the use of a panel of genetically diverse mouse inbred strains, we developed a drug screening platform aimed at examin...

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Bibliografiske detaljer
Udgivet i:Pharmgenomics Pers Med
Main Authors: Frick, Amber, Fedoriw, Yuri, Richards, Kristy, Damania, Blossom, Parks, Bethany, Suzuki, Oscar, Benton, Cristina S, Chan, Emmanuel, Thomas, Russell S, Wiltshire, Tim
Format: Artigo
Sprog:Inglês
Udgivet: Dove Medical Press 2015
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Original Research
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4397719/
https://ncbi.nlm.nih.gov/pubmed/25897258
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/PGPM.S73312
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