A cellular genetics approach identifies gene-drug interactions and pinpoints drug toxicity pathway nodes

New approaches to toxicity testing have incorporated high-throughput screening across a broad-range of in vitro assays to identify potential key events in response to chemical or drug treatment. To date, these approaches have primarily utilized repurposed drug discovery assays. In this study, we des...

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Detalhes bibliográficos
Main Authors: Suzuki, Oscar T., Frick, Amber, Parks, Bethany B., Trask, O. Joseph, Butz, Natasha, Steffy, Brian, Chan, Emmanuel, Scoville, David K., Healy, Eric, Benton, Cristina, McQuaid, Patricia E., Thomas, Russell S., Wiltshire, Tim
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2014
Assuntos:
Genetics
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4148776/
https://ncbi.nlm.nih.gov/pubmed/25221565
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fgene.2014.00272
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