A cellular genetics approach identifies gene-drug interactions and pinpoints drug toxicity pathway nodes

New approaches to toxicity testing have incorporated high-throughput screening across a broad-range of in vitro assays to identify potential key events in response to chemical or drug treatment. To date, these approaches have primarily utilized repurposed drug discovery assays. In this study, we des...

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Hlavní autoři: Suzuki, Oscar T., Frick, Amber, Parks, Bethany B., Trask, O. Joseph, Butz, Natasha, Steffy, Brian, Chan, Emmanuel, Scoville, David K., Healy, Eric, Benton, Cristina, McQuaid, Patricia E., Thomas, Russell S., Wiltshire, Tim
Médium: Artigo
Jazyk:Inglês
Vydáno: Frontiers Media S.A. 2014
Témata:
Genetics
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4148776/
https://ncbi.nlm.nih.gov/pubmed/25221565
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fgene.2014.00272
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