Identifying genes that mediate anthracyline toxicity in immune cells

The role of the immune system in response to chemotherapeutic agents remains elusive. The interpatient variability observed in immune and chemotherapeutic cytotoxic responses is likely, at least in part, due to complex genetic differences. Through the use of a panel of genetically diverse mouse inbr...

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Bibliographic Details
Published in:Front Pharmacol
Main Authors: Frick, Amber, Suzuki, Oscar T., Benton, Cristina, Parks, Bethany, Fedoriw, Yuri, Richards, Kristy L., Thomas, Russell S., Wiltshire, Tim
Format: Artigo
Language:Inglês
Published: Frontiers Media S.A. 2015
Subjects:
Pharmacology
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4398020/
https://ncbi.nlm.nih.gov/pubmed/25926793
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2015.00062
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