A cellular genetics approach identifies gene-drug interactions and pinpoints drug toxicity pathway nodes

New approaches to toxicity testing have incorporated high-throughput screening across a broad-range of in vitro assays to identify potential key events in response to chemical or drug treatment. To date, these approaches have primarily utilized repurposed drug discovery assays. In this study, we des...

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Bibliographische Detailangaben
Hauptverfasser: Suzuki, Oscar T., Frick, Amber, Parks, Bethany B., Trask, O. Joseph, Butz, Natasha, Steffy, Brian, Chan, Emmanuel, Scoville, David K., Healy, Eric, Benton, Cristina, McQuaid, Patricia E., Thomas, Russell S., Wiltshire, Tim
Format: Artigo
Sprache:Inglês
Veröffentlicht: Frontiers Media S.A. 2014
Schlagworte:
Genetics
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4148776/
https://ncbi.nlm.nih.gov/pubmed/25221565
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fgene.2014.00272
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