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A possible role for AMP-activated protein kinase activated by metformin and AICAR in human granulosa cells
BACKGROUND: Women with polycystic ovary syndrome (PCOS) are generally insulin- resistant and are consequently often treated with metformin. We investigated the effect of metformin and AICAR on the AMP-activated protein kinase (AMPK) pathway. METHODS: We evaluated the effects of 5-amino-imidazole-4-c...
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| Опубликовано в: : | Reprod Biol Endocrinol |
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| Главные авторы: | , , , |
| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
BioMed Central
2015
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4397678/ https://ncbi.nlm.nih.gov/pubmed/25889494 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12958-015-0023-2 |
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