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Activation of AMP-Activated Protein Kinase by AICAR Prevents Leucine Stimulated Protein Synthesis in Rat Skeletal Muscle

Several stress conditions are characterized by activation of 5′-AMP-protein kinase (AMPK) and the development of leucine resistance in skeletal muscle. The present study determined whether direct activation of the AMPK by AICAR prevents the characteristic leucine-induced increase in protein synthesi...

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Detalhes bibliográficos
Main Authors: Pruznak, Anne M., Kazi, Abid A., Frost, Robert A., Vary, Thomas C., Lang, Charles H.
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2596722/
https://ncbi.nlm.nih.gov/pubmed/18806097
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