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SEPSIS-INDUCED ALTERATIONS IN PROTEIN-PROTEIN INTERACTIONS WITHIN mTOR COMPLEX 1 AND THE MODULATING EFFECT OF LEUCINE ON MUSCLE PROTEIN SYNTHESIS
Sepsis-induced muscle atrophy is produced in part by decreased protein synthesis mediated by inhibition of mTOR (mammalian target of rapamycin). The present study tests the hypothesis that alteration of specific protein-protein interactions within the mTORC1 (mTOR complex 1) contributes to the decre...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2995824/ https://ncbi.nlm.nih.gov/pubmed/20577146 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/SHK.0b013e3181ecb57c |
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