BMP signaling mediated by constitutively active Activin type 1 receptor (ACVR1) results in ectopic bone formation localized to distal extremity joints

BMP signaling mediated by ACVR1 plays a critical role for development of multiple structures including the cardiovascular and skeletal systems. While deficient ACVR1 signaling impairs normal embryonic development, hyperactive ACVR1 function (R206H in humans and Q207D mutation in mice, ca-ACVR1) resu...

Descripció completa

Guardat en:
Dades bibliogràfiques
Publicat a:Dev Biol
Autors principals: Agarwal, Shailesh, Loder, Shawn J., Brownley, Cameron, Eboda, Oluwatobi, Peterson, Jonathan, Hayano, Satoru, Wu, Bingrou, Zhao, Bin, Kaartinen, Vesa, Wong, Victor C., Mishina, Yuji, Levi, Benjamin
Format: Artigo
Idioma:Inglês
Publicat: 2015
Matèries:
Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4397658/
https://ncbi.nlm.nih.gov/pubmed/25722188
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ydbio.2015.02.011
Etiquetes: Afegir etiqueta
Sense etiquetes, Sigues el primer a etiquetar aquest registre!

Ítems similars