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Engagement of the GABA to KCC2 Signaling Pathway Contributes to the Analgesic Effects of A(3)AR Agonists in Neuropathic Pain

More than 1.5 billion people worldwide suffer from chronic pain, yet current treatment strategies often lack efficacy or have deleterious side effects in patients. Adenosine is an inhibitory neuromodulator that was previously thought to mediate antinociception through the A(1) and A(2A) receptor sub...

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Detalles Bibliográficos
Publicado en:J Neurosci
Main Authors: Ford, Amanda, Castonguay, Annie, Cottet, Martin, Little, Joshua W., Chen, Zhoumou, Symons-Liguori, Ashley M., Doyle, Timothy, Egan, Terrance M., Vanderah, Todd W., De Koninck, Yves, Tosh, Dilip K., Jacobson, Kenneth A., Salvemini, Daniela
Formato: Artigo
Idioma:Inglês
Publicado: Society for Neuroscience 2015
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4397603/
https://ncbi.nlm.nih.gov/pubmed/25878279
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.4495-14.2015
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