Engagement of the GABA to KCC2 Signaling Pathway Contributes to the Analgesic Effects of A(3)AR Agonists in Neuropathic Pain

More than 1.5 billion people worldwide suffer from chronic pain, yet current treatment strategies often lack efficacy or have deleterious side effects in patients. Adenosine is an inhibitory neuromodulator that was previously thought to mediate antinociception through the A(1) and A(2A) receptor sub...

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Bibliografiset tiedot
Julkaisussa:J Neurosci
Päätekijät: Ford, Amanda, Castonguay, Annie, Cottet, Martin, Little, Joshua W., Chen, Zhoumou, Symons-Liguori, Ashley M., Doyle, Timothy, Egan, Terrance M., Vanderah, Todd W., De Koninck, Yves, Tosh, Dilip K., Jacobson, Kenneth A., Salvemini, Daniela
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Society for Neuroscience 2015
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Articles
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC4397603/
https://ncbi.nlm.nih.gov/pubmed/25878279
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.4495-14.2015
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