Engagement of the GABA to KCC2 Signaling Pathway Contributes to the Analgesic Effects of A(3)AR Agonists in Neuropathic Pain

More than 1.5 billion people worldwide suffer from chronic pain, yet current treatment strategies often lack efficacy or have deleterious side effects in patients. Adenosine is an inhibitory neuromodulator that was previously thought to mediate antinociception through the A(1) and A(2A) receptor sub...

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Detalhes bibliográficos
Publicado no:J Neurosci
Main Authors: Ford, Amanda, Castonguay, Annie, Cottet, Martin, Little, Joshua W., Chen, Zhoumou, Symons-Liguori, Ashley M., Doyle, Timothy, Egan, Terrance M., Vanderah, Todd W., De Koninck, Yves, Tosh, Dilip K., Jacobson, Kenneth A., Salvemini, Daniela
Formato: Artigo
Idioma:Inglês
Publicado em: Society for Neuroscience 2015
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Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4397603/
https://ncbi.nlm.nih.gov/pubmed/25878279
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.4495-14.2015
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