Non-Aggregating Tau Phosphorylation by Cyclin-Dependent Kinase 5 Contributes to Motor Neuron Degeneration in Spinal Muscular Atrophy

Mechanisms underlying motor neuron degeneration in spinal muscular atrophy (SMA), the leading inherited cause of infant mortality, remain largely unknown. Many studies have established the importance of hyperphosphorylation of the microtubule-associated protein tau in various neurodegenerative disor...

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Bibliografiska uppgifter
I publikationen:J Neurosci
Huvudupphovsmän: Miller, Nimrod, Feng, Zhihua, Edens, Brittany M., Yang, Ben, Shi, Han, Sze, Christie C., Hong, Benjamin Taige, Su, Susan C., Cantu, Jorge A., Topczewski, Jacek, Crawford, Thomas O., Ko, Chien-Ping, Sumner, Charlotte J., Ma, Long, Ma, Yong-Chao
Materialtyp: Artigo
Språk:Inglês
Publicerad: Society for Neuroscience 2015
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Articles
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC4397602/
https://ncbi.nlm.nih.gov/pubmed/25878277
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.3716-14.2015
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