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Targeted nanoparticles containing the proresolving peptide Ac2-26 protect against advanced atherosclerosis in hypercholesterolemic mice

Chronic, nonresolving inflammation is a critical factor in the clinical progression of advanced atherosclerotic lesions. In the normal inflammatory response, resolution is mediated by several agonists, among which is the glucocorticoid-regulated protein called annexin A1. The proresolving actions of...

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Библиографические подробности
Опубликовано в: :Sci Transl Med
Главные авторы: Fredman, Gabrielle, Kamaly, Nazila, Spolitu, Stefano, Milton, Jaclyn, Ghorpade, Devram, Chiasson, Raymond, Kuriakose, George, Perretti, Mauro, Farokzhad, Omid, Tabas, Ira
Формат: Artigo
Язык:Inglês
Опубликовано: 2015
Предметы:
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC4397585/
https://ncbi.nlm.nih.gov/pubmed/25695999
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/scitranslmed.aaa1065
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