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Mechanism and Inhibition of saFabI, the Enoyl Reductase from Staphylococcus aureus

About one third of the world’s population carries Staphylococcus aureus. The recent emergence of extreme drug resistant strains that are resistant to the “antibiotic of last resort”, vancomycin, has caused a further increase in the pressing need to discover new drugs against this organism. The S. au...

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Publicado en:Biochemistry
Autores principales: Xu, Hua, Sullivan, Todd, Sekiguchi, Jun-ichiro, Kirikae, Teruo, Ojima, Iwao, Mao, Weimin, Rock, Fernando L, Alley, M. R. K., Johnson, Francis, Walker, Stephen G., Tonge, Peter J.
Formato: Artigo
Lenguaje:Inglês
Publicado: 2008
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4397500/
https://ncbi.nlm.nih.gov/pubmed/18335995
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi800023a
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