Kupffer Cell Suppression of CD8(+) T cells in Human Hepatocellular Carcinoma is Mediated by B7-H1/PD-1 Interactions

B7-H1 is a recently identified B7 family member that along with one of its receptors, PD-1 has been involved in multiple immunopathological scenarios. However, the nature of B7-H1 and PD-1 in human hepatocellular carcinoma (HCC) remains poorly defined. We investigated the expression and functional r...

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Bibliographic Details
Published in:Cancer Res
Main Authors: Wu, Ke, Kryczek, Ilona, Chen, Lieping, Zou, Weiping, Welling, Theodore H.
Format: Artigo
Language:Inglês
Published: 2009
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4397483/
https://ncbi.nlm.nih.gov/pubmed/19826049
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-09-0901
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