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Tumor-induced Immune Suppression of In Vivo T Effector Cell Priming is Mediated by the B7-H1/PD-1 Axis and TGF-β
We have generated effector T cells from tumor-draining lymph nodes that are efficacious in adoptive immunotherapy. We now examined the effect of concomitant tumors on the generation of effector T cells. We inoculated MCA 205 in the flanks of normal mice and mice bearing MCA 205 lung metastases. Tumo...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2008
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3094850/ https://ncbi.nlm.nih.gov/pubmed/18593946 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-07-6598 |
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