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B cells take the front seat: Dysregulated B cell signals orchestrate loss of tolerance and autoantibody production
A significant proportion of autoimmune-associated genetic variants are expressed in B cells, suggesting that B cells may play multiple roles in autoimmune pathogenesis. In this review, we highlight recent studies demonstrating that even modest alterations in B cell signaling are sufficient to promot...
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| Publicado en: | Curr Opin Immunol |
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| Main Authors: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
2015
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4397155/ https://ncbi.nlm.nih.gov/pubmed/25679954 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.coi.2015.01.018 |
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