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The long and the short of it: insights into the cellular source of autoantibodies as revealed by B cell depletion therapy

High titers of pathogenic autoantibodies are a hallmark of many autoimmune diseases. However, much remains unknown about the self-reactive plasma cells that are key mediators of disease. We propose a model in which the varying efficacy of precursor B cell depletion for the treatment of humoral autoi...

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Pubblicato in:Curr Opin Immunol
Autori principali: Hale, Malika, Rawlings, David J., Jackson, Shaun W.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2018
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6289281/
https://ncbi.nlm.nih.gov/pubmed/30390507
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.coi.2018.10.008
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