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B cell depletion therapies in autoimmune disease: advances and mechanistic insights

In the past 15 years, B cells have been rediscovered to be not merely bystanders but rather active participants in autoimmune aetiology. This has been fuelled in part by the clinical success of B cell depletion therapies (BCDTs). Originally conceived as a method of eliminating cancerous B cells, BCD...

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Detalhes bibliográficos
Publicado no:Nat Rev Drug Discov
Main Authors: Lee, Dennis S. W., Rojas, Olga L., Gommerman, Jennifer L.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7737718/
https://ncbi.nlm.nih.gov/pubmed/33324003
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41573-020-00092-2
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