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Designing Chimeric Antigen Receptors to Effectively and Safely Target Tumors
The adoptive transfer of T cells engineered to express artificial chimeric antigen receptors (CARs) that target a tumor cell surface molecule has emerged as an exciting new approach for cancer immunotherapy. Clinical trials in patients with advanced B cell malignancies treated with CD19-specific CAR...
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| Veröffentlicht in: | Curr Opin Immunol |
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| Hauptverfasser: | , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2015
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4397136/ https://ncbi.nlm.nih.gov/pubmed/25621840 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.coi.2015.01.002 |
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