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Designing Chimeric Antigen Receptors to Effectively and Safely Target Tumors

The adoptive transfer of T cells engineered to express artificial chimeric antigen receptors (CARs) that target a tumor cell surface molecule has emerged as an exciting new approach for cancer immunotherapy. Clinical trials in patients with advanced B cell malignancies treated with CD19-specific CAR...

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Bibliografiske detaljer
Udgivet i:Curr Opin Immunol
Main Authors: Jensen, Michael C., Riddell, Stanley R.
Format: Artigo
Sprog:Inglês
Udgivet: 2015
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4397136/
https://ncbi.nlm.nih.gov/pubmed/25621840
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.coi.2015.01.002
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