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The RanGEF Bj1 promotes Prospero nuclear export and neuroblast self-renewal

Drosophila larval neuroblasts are a model system for studying stem cell self-renewal and differentiation. Here we report a novel role for the Drosophila gene Bj1 in promoting larval neuroblast self-renewal. Bj1 is the guanine-nucleotide exchange factor for Ran GTPase, which regulates nuclear import/...

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Publicat a:Dev Neurobiol
Autors principals: Joy, Tasha, Hirono, Keiko, Doe, Chris Q.
Format: Artigo
Idioma:Inglês
Publicat: 2014
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4397115/
https://ncbi.nlm.nih.gov/pubmed/25312250
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/dneu.22237
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