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Detection and Analysis of DNA Damage in Mouse Skeletal Muscle In Situ Using the TUNEL Method

Terminal deoxynucleotidyl transferase (TdT) deoxyuridine triphosphate (dUTP) nick end labeling (TUNEL) is the method of using the TdT enzyme to covalently attach a tagged form of dUTP to 3’ ends of double- and single-stranded DNA breaks in cells. It is a reliable and useful method to detect DNA dama...

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Detalhes bibliográficos
Publicado no:J Vis Exp
Main Authors: Fayzullina, Saniya, Martin, Lee J.
Formato: Artigo
Idioma:Inglês
Publicado em: MyJove Corporation 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4396960/
https://ncbi.nlm.nih.gov/pubmed/25549099
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3791/52211
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