Chronically ischemic mouse skeletal muscle exhibits myopathy in association with mitochondrial dysfunction and oxidative damage

A myopathy characterized by mitochondrial pathology and oxidative stress is present in patients with peripheral arterial disease (PAD). Patients with PAD differ in disease severity, mode of presentation, and presence of comorbid conditions. In this study, we used a mouse model of hindlimb ischemia t...

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Главные авторы: Pipinos, Iraklis I., Swanson, Stanley A., Zhu, Zhen, Nella, Aikaterini A., Weiss, Dustin J., Gutti, Tanuja L., McComb, Rodney D., Baxter, B. Timothy, Lynch, Thomas G., Casale, George P.
Формат: Artigo
Язык:Inglês
Опубликовано: American Physiological Society 2008
Предметы:
Translational Physiology
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC2494805/
https://ncbi.nlm.nih.gov/pubmed/18480238
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpregu.90374.2008
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