Targeted Knockdown of RNA-Binding Protein TIAR for Promoting Self-Renewal and Attenuating Differentiation of Mouse Embryonic Stem Cells

RNA-binding protein TIAR has been suggested to mediate the translational silencing of ARE-containing mRNAs. To analyze the functions of TIAR, we established RNAi and genetic rescue assays. We evaluated the expression of neuroectoderm markers Pax6 and nestin, mesoderm markers brachyury and Flk1, and...

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發表在:Stem Cells Int
Main Authors: Geng, Zhe, Li, Ping, Tan, Li, Song, Houyan
格式: Artigo
語言:Inglês
出版: Hindawi Publishing Corporation 2015
主題:
Research Article
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC4396887/
https://ncbi.nlm.nih.gov/pubmed/25918534
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2015/657325
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