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Targeted Knockdown of RNA-Binding Protein TIAR for Promoting Self-Renewal and Attenuating Differentiation of Mouse Embryonic Stem Cells

RNA-binding protein TIAR has been suggested to mediate the translational silencing of ARE-containing mRNAs. To analyze the functions of TIAR, we established RNAi and genetic rescue assays. We evaluated the expression of neuroectoderm markers Pax6 and nestin, mesoderm markers brachyury and Flk1, and...

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Detalhes bibliográficos
Publicado no:Stem Cells Int
Main Authors: Geng, Zhe, Li, Ping, Tan, Li, Song, Houyan
Formato: Artigo
Idioma:Inglês
Publicado em: Hindawi Publishing Corporation 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4396887/
https://ncbi.nlm.nih.gov/pubmed/25918534
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2015/657325
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