Oncogenic HER2 fusions in gastric cancer

BACKGROUND: Genetic amplification of HER2 drives tumorigenesis and cancer progression in a subset of patients with gastric cancer (GC), and treatment with trastuzumab, a humanized HER2-neutralizing antibody, improves the overall survival rate of HER2-positive patients. However, a considerable portio...

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Detalhes bibliográficos
Publicado no:J Transl Med
Main Authors: Yu, De-Hua, Tang, Lili, Dong, Hua, Dong, Zhengwei, Zhang, Lianhai, Fu, Jiangang, Su, Xinying, Zhang, Tianwei, Fu, Haihua, Han, Lu, Xie, Liang, Chen, Hao, Qian, Ziliang, Zhu, Guanshan, Wang, Jia, Ye, Qingqing, Zhang, Jingchuan, Yin, Xiaolu, Zhang, Xiaolin, Ji, Jiafu, Ji, Qunsheng
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2015
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4396883/
https://ncbi.nlm.nih.gov/pubmed/25889497
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12967-015-0476-2
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