Identification and validation of dysregulated MAPK7 (ERK5) as a novel oncogenic target in squamous cell lung and esophageal carcinoma

BACKGROUND: MAPK7/ERK5 (extracellular-signal-regulated kinase 5) functions within a canonical three-tiered MAPK (mitogen activated protein kinase) signaling cascade comprising MEK (MAPK/ERK kinase) 5, MEKK(MEK kinase) 2/3 and ERK5 itself. Despite being the least well studied of the MAPK-modules, evi...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:BMC Cancer
Prif Awduron: Gavine, Paul R., Wang, Mei, Yu, Dehua, Hu, Eva, Huang, Chunlei, Xia, Jenny, Su, Xinying, Fan, Joan, Zhang, Tianwei, Ye, Qingqing, Zheng, Li, Zhu, Guanshan, Qian, Ziliang, Luo, Qingquan, Hou, Ying Yong, Ji, Qunsheng
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: BioMed Central 2015
Pynciau:
Research Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC4453990/
https://ncbi.nlm.nih.gov/pubmed/26040563
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12885-015-1455-y
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