Identification and validation of dysregulated MAPK7 (ERK5) as a novel oncogenic target in squamous cell lung and esophageal carcinoma

BACKGROUND: MAPK7/ERK5 (extracellular-signal-regulated kinase 5) functions within a canonical three-tiered MAPK (mitogen activated protein kinase) signaling cascade comprising MEK (MAPK/ERK kinase) 5, MEKK(MEK kinase) 2/3 and ERK5 itself. Despite being the least well studied of the MAPK-modules, evi...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:BMC Cancer
Main Authors: Gavine, Paul R., Wang, Mei, Yu, Dehua, Hu, Eva, Huang, Chunlei, Xia, Jenny, Su, Xinying, Fan, Joan, Zhang, Tianwei, Ye, Qingqing, Zheng, Li, Zhu, Guanshan, Qian, Ziliang, Luo, Qingquan, Hou, Ying Yong, Ji, Qunsheng
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2015
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4453990/
https://ncbi.nlm.nih.gov/pubmed/26040563
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12885-015-1455-y
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados