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Attenuation of traumatic brain injury-induced cognitive impairment in mice by targeting increased cytokine levels with a small molecule experimental therapeutic

BACKGROUND: Evidence from clinical studies and preclinical animal models suggests that proinflammatory cytokine overproduction is a potential driving force for pathology progression in traumatic brain injury (TBI). This raises the possibility that selective targeting of the overactive cytokine respo...

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Detalhes bibliográficos
Publicado no:J Neuroinflammation
Main Authors: Bachstetter, Adam D, Webster, Scott J, Goulding, Danielle S, Morton, Jonathan E, Watterson, D Martin, Van Eldik, Linda J
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4396836/
https://ncbi.nlm.nih.gov/pubmed/25886256
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12974-015-0289-5
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