Genetic knockout of myosin light chain kinase (MLCK210) prevents cerebral microhemorrhages and attenuates neuroinflammation in a mouse model of vascular cognitive impairment and dementia

The blood-brain barrier (BBB) is critical in maintenance of brain homeostasis, and loss of its functional integrity is a key feature across a broad range of neurological insults. This includes both acute injuries such as traumatic brain injury and stroke, as well as more chronic pathologies associat...

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Vydáno v:GeroScience
Hlavní autoři: Braun, David J., Bachstetter, Adam D., Sudduth, Tiffany L., Wilcock, Donna M., Watterson, D. Martin, Van Eldik, Linda J.
Médium: Artigo
Jazyk:Inglês
Vydáno: Springer International Publishing 2019
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Original Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6885026/
https://ncbi.nlm.nih.gov/pubmed/31104189
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11357-019-00072-4
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