Human prion protein sequence elements impede cross-species chronic wasting disease transmission

Chronic wasting disease (CWD) is a fatal prion disease of North American deer and elk and poses an unclear risk for transmission to humans. Human exposure to CWD occurs through hunting activities and consumption of venison from prion-infected animals. Although the amino acid residues of the prion pr...

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Detalhes bibliográficos
Publicado no:J Clin Invest
Main Authors: Kurt, Timothy D., Jiang, Lin, Fernández-Borges, Natalia, Bett, Cyrus, Liu, Jun, Yang, Tom, Spraker, Terry R., Castilla, Joaquín, Eisenberg, David, Kong, Qingzhong, Sigurdson, Christina J.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 2015
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Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4396485/
https://ncbi.nlm.nih.gov/pubmed/25705888
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI79408
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