Brain metastatic cancer cells release microRNA-181c-containing extracellular vesicles capable of destructing blood–brain barrier

Brain metastasis is an important cause of mortality in breast cancer patients. A key event during brain metastasis is the migration of cancer cells through blood–brain barrier (BBB). However, the molecular mechanism behind the passage through this natural barrier remains unclear. Here we show that c...

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Bibliografiske detaljer
Udgivet i:Nat Commun
Main Authors: Tominaga, Naoomi, Kosaka, Nobuyoshi, Ono, Makiko, Katsuda, Takeshi, Yoshioka, Yusuke, Tamura, Kenji, Lötvall, Jan, Nakagama, Hitoshi, Ochiya, Takahiro
Format: Artigo
Sprog:Inglês
Udgivet: Nature Pub. Group 2015
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4396394/
https://ncbi.nlm.nih.gov/pubmed/25828099
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms7716
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