Brain metastatic cancer cells release microRNA-181c-containing extracellular vesicles capable of destructing blood–brain barrier

Brain metastasis is an important cause of mortality in breast cancer patients. A key event during brain metastasis is the migration of cancer cells through blood–brain barrier (BBB). However, the molecular mechanism behind the passage through this natural barrier remains unclear. Here we show that c...

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Detalhes bibliográficos
Publicado no:Nat Commun
Main Authors: Tominaga, Naoomi, Kosaka, Nobuyoshi, Ono, Makiko, Katsuda, Takeshi, Yoshioka, Yusuke, Tamura, Kenji, Lötvall, Jan, Nakagama, Hitoshi, Ochiya, Takahiro
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Pub. Group 2015
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4396394/
https://ncbi.nlm.nih.gov/pubmed/25828099
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms7716
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