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Brain metastatic cancer cells release microRNA-181c-containing extracellular vesicles capable of destructing blood–brain barrier

Brain metastasis is an important cause of mortality in breast cancer patients. A key event during brain metastasis is the migration of cancer cells through blood–brain barrier (BBB). However, the molecular mechanism behind the passage through this natural barrier remains unclear. Here we show that c...

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Podrobná bibliografie
Vydáno v:Nat Commun
Hlavní autoři: Tominaga, Naoomi, Kosaka, Nobuyoshi, Ono, Makiko, Katsuda, Takeshi, Yoshioka, Yusuke, Tamura, Kenji, Lötvall, Jan, Nakagama, Hitoshi, Ochiya, Takahiro
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Pub. Group 2015
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4396394/
https://ncbi.nlm.nih.gov/pubmed/25828099
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms7716
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