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DCA promotes progression of neuroblastoma tumors in nude mice

Even in the presence of oxygen most cancer cells convert glucose to lactate via pyruvate instead of performing oxidative phosphorylation (aerobic glycolysis-Warburg effect). Thus, it has been considered to shift pyruvate - the metabolite of aerobic glycolysis - to acetylCoA by activation of pyruvate...

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Bibliografiska uppgifter
I publikationen:Am J Cancer Res
Huvudupphovsmän: Feuerecker, Benedikt, Seidl, Christof, Pirsig, Sabine, Bruchelt, Gernot, Senekowitsch-Schmidtke, Reingard
Materialtyp: Artigo
Språk:Inglês
Publicerad: e-Century Publishing Corporation 2015
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Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC4396043/
https://ncbi.nlm.nih.gov/pubmed/25973318
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