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DCA promotes progression of neuroblastoma tumors in nude mice

Even in the presence of oxygen most cancer cells convert glucose to lactate via pyruvate instead of performing oxidative phosphorylation (aerobic glycolysis-Warburg effect). Thus, it has been considered to shift pyruvate - the metabolite of aerobic glycolysis - to acetylCoA by activation of pyruvate...

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Detalhes bibliográficos
Publicado no:Am J Cancer Res
Main Authors: Feuerecker, Benedikt, Seidl, Christof, Pirsig, Sabine, Bruchelt, Gernot, Senekowitsch-Schmidtke, Reingard
Formato: Artigo
Idioma:Inglês
Publicado em: e-Century Publishing Corporation 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4396043/
https://ncbi.nlm.nih.gov/pubmed/25973318
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