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Efficient representation of uncertainty in multiple sequence alignments using directed acyclic graphs
BACKGROUND: A standard procedure in many areas of bioinformatics is to use a single multiple sequence alignment (MSA) as the basis for various types of analysis. However, downstream results may be highly sensitive to the alignment used, and neglecting the uncertainty in the alignment can lead to sig...
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Publié dans: | BMC Bioinformatics |
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Auteurs principaux: | , , , , , |
Format: | Artigo |
Langue: | Inglês |
Publié: |
BioMed Central
2015
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Sujets: | |
Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4395974/ https://ncbi.nlm.nih.gov/pubmed/25888064 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12859-015-0516-1 |
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