Loss of T Cell and B Cell Quiescence Precedes the Onset of Microbial Flora-Dependent Wasting Disease and Intestinal Inflammation in Gimap5-Deficient Mice

Homeostatic control of the immune system involves mechanisms that ensure the self-tolerance, survival and quiescence of hematopoietic-derived cells. In this study, we demonstrate that the GTPase of immunity associated protein (Gimap)5 regulates these processes in lymphocytes and hematopoietic progen...

תיאור מלא

שמור ב:
מידע ביבליוגרפי
הוצא לאור ב:J Immunol
Main Authors: Barnes, Michael J., Aksoylar, Halil, Krebs, Philippe, Bourdeau, Tristan, Arnold, Carrie N., Xia, Yu, Khovananth, Kevin, Engel, Isaac, Sovath, Sosathya, Lampe, Kristin, Laws, Eleana, Saunders, Amy, Butcher, Geoffrey W., Kronenberg, Mitchell, Steinbrecher, Kris, Hildeman, David, Grimes, H. Leighton, Beutler, Bruce, Hoebe, Kasper
פורמט: Artigo
שפה:Inglês
יצא לאור: 2010
נושאים:
Article
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC4395861/
https://ncbi.nlm.nih.gov/pubmed/20190135
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.0903164
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