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High Capsid–Genome Correlation Facilitates Creation of AAV Libraries for Directed Evolution
Directed evolution of adeno-associated virus (AAV) through successive rounds of phenotypic selection is a powerful method to isolate variants with improved properties from large libraries of capsid mutants. Importantly, AAV libraries used for directed evolution are based on the “natural” AAV genome...
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| Publicado no: | Mol Ther |
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| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4395795/ https://ncbi.nlm.nih.gov/pubmed/25586687 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mt.2015.3 |
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