MULTIVALENT DISPLAY OF PENDANT PRO-APOPTOTIC PEPTIDES INCREASES CYTOTOXIC ACTIVITY

Several cationic antimicrobial peptides have been investigated as potential anti-cancer drugs due to their demonstrated selective toxicity towards cancer cells relative to normal cells. For example, intracellular delivery of KLA, a pro-apoptotic peptide, results in toxicity against a variety of canc...

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Bibliografiske detaljer
Udgivet i:J Control Release
Main Authors: Chu, David S.H., Bocek, Michael J., Shi, Julie, Ta, Anh, Ngambenjawong, Chayanon, Rostomily, Robert C., Pun, Suzie H.
Format: Artigo
Sprog:Inglês
Udgivet: 2015
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4395534/
https://ncbi.nlm.nih.gov/pubmed/25596326
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jconrel.2015.01.013
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