MULTIVALENT DISPLAY OF PENDANT PRO-APOPTOTIC PEPTIDES INCREASES CYTOTOXIC ACTIVITY

Several cationic antimicrobial peptides have been investigated as potential anti-cancer drugs due to their demonstrated selective toxicity towards cancer cells relative to normal cells. For example, intracellular delivery of KLA, a pro-apoptotic peptide, results in toxicity against a variety of canc...

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Bibliographic Details
Published in:	J Control Release
Main Authors:	Chu, David S.H., Bocek, Michael J., Shi, Julie, Ta, Anh, Ngambenjawong, Chayanon, Rostomily, Robert C., Pun, Suzie H.
Format:	Artigo
Language:	Inglês
Published:	2015
Subjects:	Article
Online Access:	https://ncbi.nlm.nih.gov/pmc/articles/PMC4395534/ https://ncbi.nlm.nih.gov/pubmed/25596326 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jconrel.2015.01.013
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MULTIVALENT DISPLAY OF PENDANT PRO-APOPTOTIC PEPTIDES INCREASES CYTOTOXIC ACTIVITY

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