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Engineering an affinity-enhanced peptide through optimization of cyclization chemistry

Peptide cyclization is a strategy used to improve stability and/or activity of peptides. The most commonly used cyclization method is disulfide bridge formation of cysteine-containing peptides as typically found in nature. Over the years, an increasing number of alternative chemistries for peptide c...

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Detalhes bibliográficos
Publicado no:Bioconjug Chem
Main Authors: Ngambenjawong, Chayanon, Pineda, Julio Marco B., Pun, Suzie H.
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5678939/
https://ncbi.nlm.nih.gov/pubmed/27779387
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.bioconjchem.6b00502
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